A Chinese research team has found a new bat coronavirus that poses a risk of animal-to-human transmission through the same receptor as Covid-19. The study was led by renowned virologist Shi Zhengli, identifying a new lineage from HKU5 coronaviruses. This discovery emphasizes the ongoing threat posed by coronaviruses originating from bats and highlights the necessity for continued monitoring.
A recent study conducted by a Chinese research team has identified a new bat coronavirus with the potential to infect humans through the same pathway as the virus responsible for Covid-19. This investigation was led by Shi Zhengli, renowned as the ‘batwoman’ for her extensive research on coronaviruses, in collaboration with the Guangzhou Academy of Sciences, Wuhan University, and the Wuhan Institute of Virology. Zhengli’s work has garnered significant attention due to the ongoing debate regarding the origins of Covid-19, with some postulating a possible lab leak from Wuhan.
The newly discovered virus is part of the HKU5 coronavirus lineage initially found in the Japanese pipistrelle bat located in Hong Kong. This novel virus belongs to the merbecovirus subgenus, which includes the pathogen that causes Middle East Respiratory Syndrome (MERS). The ability of this virus to bind with the human angiotensin-converting enzyme 2 (ACE2) receptor allows it to penetrate human cells, much like SARS-CoV-2, the virus resulting in Covid-19.
Given the similarities in receptor usage, the findings underscore a potential risk for animal-to-human transmission, prompting further scrutiny and research in the virology field. While no consensus has emerged regarding the origins of the Covid-19 virus, data do indicate a natural transfer of coronaviruses from bats to humans through intermediate animal hosts, although Zhengli has refuted claims implicating the Wuhan Institute in the outbreak.
In conclusion, the identification of a new bat coronavirus with similarities to the SARS-CoV-2 virus raises significant concerns for potential zoonotic transmission to humans. Led by Shi Zhengli and her team, the research highlights the importance of ongoing surveillance of bat coronaviruses, particularly given their capability to use the same human receptors as the virus causing Covid-19. Such discoveries are vital for preventing future outbreaks and enhancing global health security.
Original Source: www.scmp.com
